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Effect and efficacy:
Valsartan hydrochlorothiazide tablets are used to treat mild to moderate essential hypertension where a single drug cannot adequately control blood pressure.

Usage and dosage:
The recommended dose of valsartan monotherapy is 80 mg, once a day. When the antihypertensive effect is unsatisfactory, the daily dose can be increased to 160 mg. The effective dose of hydrochlorothiazide is 12.5-50 mg per day, once a day. In order to reduce dose-independent adverse reactions, combined medication is usually considered only when monotherapy cannot achieve satisfactory results. During the combined use of valsartan and hydrochlorothiazide, the dose of each drug needs to be adjusted. When the dose adjustment is satisfactory, the same dose of this product can be used instead of the combined medication. Dose adjustment: Each tablet of this product contains 80 mg of valsartan and 12.5 mg of hydrochlorothiazide. When valsartan monotherapy cannot satisfactorily control blood pressure, hydrochlorothiazide 25mg once a day cannot satisfactorily control blood pressure or hypokalemia occurs, this product (containing valsartan 80mg/hydrochlorothiazide 12.5mg) can be used instead. One tablet each time, once a day, and the maximum antihypertensive effect can be achieved within 2 to 4 weeks of medication. For patients with mild to moderate renal failure (creatinine clearance ≥30 ml/min) or mild to moderate liver failure, no dose adjustment is required.

Adverse reactions:
Common adverse reactions of the combined use of valsartan and hydrochlorothiazide include headache and dizziness. Common adverse reactions in patients receiving single thiazide diuretics (including hydrochlorothiazide) include hypokalemia.

Drug contraindications:
Allergic to this product is prohibited. It is prohibited during pregnancy and lactation. It is used with caution by athletes and children.

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