Valganciclovir hydrochloride tablets are an antiviral drug, which is mainly used clinically to treat cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS); and to prevent CMV infection in high-risk solid organ transplant patients.
Valganciclovir is the L-valyl ester (prodrug) of ganciclovir, which can be rapidly converted into ganciclovir by esterases in the small intestine and liver after oral administration. Ganciclovir is a synthetic analog of 2′-deoxyguanosine acid, which can inhibit the replication of human cytomegalovirus (CMV) both in vitro and in vivo.
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