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Ustekinumab Injection

Ustekinumab usually refers to ustekinumab injection, which is usually effective in treating moderate to severe plaque psoriasis, Crohn’s disease, and psoriatic arthritis, but may cause side effects such as hypersensitivity, gastrointestinal discomfort, and limb discomfort.

1. Effect

1. Moderate to severe plaque psoriasis: Ustekinumab injection is a new type of biological agent, commonly used to treat moderate to severe plaque psoriasis, which can participate in cell activities, help inhibit lymphocyte proliferation, prevent the continued expansion and thickening of skin lesions, and stabilize the patient’s condition.

2. Crohn’s disease: This disease is a chronic inflammatory granulomatous disease, and ustekinumab injection can usually participate in the binding of cytokines in chronic inflammation, block its inflammatory response, help control the development of Crohn’s disease, and improve symptoms such as abdominal pain and diarrhea.

3. Psoriatic arthritis: Ustekinumab injection can usually combine two cytokines, thereby inhibiting the role of cytokines in the pathological immune process, helping to inhibit the activity of the pathogenic factors of psoriasis, so as to avoid long-term irritation of the joints, thereby improving the swelling and pain caused by psoriatic arthritis.

2. Side effects

1. Hypersensitivity reaction: Ustekinumab injection contains highly immunogenic proteins that can directly act on the immune system without metabolism, which may stimulate the immune function, causing abnormal release of mediators by mast cells, basophils and other cells, causing hypersensitivity reactions, and patients may experience erythema, skin itching, laryngeal edema, vascular edema and other manifestations.

2. Gastrointestinal discomfort: After using ustekinumab injection, the patient’s gastrointestinal tract may be irritated, and adverse reactions such as diarrhea, nausea, and vomiting may occur.

3. Limb discomfort: After entering the blood circulation through intravenous drip, the active ingredients of ustekinumab injection can usually reach multiple parts of the body with the blood circulation, which may irritate these parts and cause symptoms such as back pain, myalgia, and joint pain.

In addition, Ustekinumab injection may also cause upper respiratory tract infection, non-infectious pneumonia and other conditions in patients, which may have a negative impact on the patient’s physical health.

The above content is for reference only. If relevant symptoms occur, it is recommended to go to the hospital for standardized diagnosis and treatment under the guidance of a doctor.