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TRAMETINIB 曲美替尼
Trametinib is a reversible inhibitor of mitogen-activated extracellular signal-regulated kinase 1 (MEK 1/2), mainly through its effect on MEK protein (the upstream regulator of the extracellular signal-related kinase (ERK) pathway) , affecting the MAPK pathway and inhibiting cell proliferation. Therefore, this product can inhibit the growth of BRAF V600 mutation-positive melanoma cells both in vivo and in vitro.
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