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Recombinant Streptokinase.

It is the first plasminogen activator discovered in the world and the first thrombolytic enzyme used as a clinical drug to treat thrombotic diseases. It is an extracellular non-enzyme protein secreted by oral-hemolytic streptococci of groups A, C, and G streptococci. It can bind to plasminogen and activate plasminogen into fibrinolytic enzyme, which has the effect of dissolving thrombus. .

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