Propylthiouracil（PTU）、6-N-Propylthiouracil（PROP）

Effects and efficacy: This product is used for various types of hyperthyroidism, especially for patients with mild to moderate thyroid enlargement. Adolescents, children and elderly patients. Patients with recurrence after thyroid surgery who are not suitable for radioactive I treatment. Preoperative preparation. As an adjuvant treatment for I radiotherapy.

Usage and dosage: This product is used to treat hyperthyroidism in adults: the starting dose is generally 300 mg per day, ranging from 150 to 400 mg depending on the severity of the disease, taken orally in divided doses, and the maximum daily dose is 600 mg. After the disease is controlled, the dose is gradually reduced, and the maintenance dose is 50 to 150 mg per day, adjusted according to the disease. For children: the starting dose is 4 mg/kg per day, taken orally in divided doses, and the maintenance dose is reduced as appropriate.

Adverse reactions: Common symptoms include headache, dizziness, joint pain, enlarged salivary glands and lymph nodes, and gastrointestinal reactions; there are also allergic reactions such as rashes and drug fever, and some rashes can develop into exfoliative dermatitis. Some patients may develop jaundice and toxic hepatitis. The most serious adverse reaction is agranulocytosis, so blood counts should be checked regularly during medication. When the white blood cell count is lower than 4×109/L or the neutrophil count is lower than 1.5×109/L, the medication should be discontinued or adjusted as directed by the doctor.

Drug contraindications:
Allergic to this product is prohibited. It is prohibited during lactation. It should be used with caution during pregnancy. It should be used with caution if liver function is damaged.