PAMIDRONATE DISODIUM INJECTION

Pamidronate disodium is an organic compound with the chemical formula C3H9NNa2O7P2. It is mainly used as a calcium regulator. Its pharmacological effects are: ① widely distributed on the surface of trabecular bone, blocking the dissolution of bone by osteoclasts; ② inhibiting osteoclasts Cell activity; ③ Inhibit the transformation of osteoclast precursors into osteoclasts. It has a very significant inhibitory effect on bone absorption and has an analgesic effect on the pain caused by osteolytic bone metastasis of cancer. Animal experiments show that this product is rapidly eliminated from the circulatory system after administration and is mainly distributed in bones, liver, intestines and tracheal cartilage. This product can remain in bone tissue for a long time