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Nimustine Hydrochloride

Functions and indications:
Used for brain tumors, digestive tract cancer (gastric cancer, liver cancer, colon cancer, rectal cancer), lung cancer, malignant lymphoma, chronic leukemia, etc.
Usage and dosage:
The dosage and dosage of this product may vary in different dosage forms and specifications. Please read the specific drug instructions for use, or follow the doctor’s advice. Nimustine hydrochloride injection: Usually, this agent is dissolved in the following dose at a ratio of 5 mg per 1 ml of injection water for intravenous or arterial administration. 1. Calculated by nimustine hydrochloride, the dosage is given according to body weight, 2-3 mg/kg once, then the drug is discontinued for 4-6 weeks according to the blood count, and the drug is given again, and so on and so forth until the clinical effect is satisfactory. 2. Calculated by nimustine hydrochloride, the dosage is 2 mg/kg once, and the drug is given every 1 week. After 2-3 times, the drug is discontinued for 4-6 weeks according to the blood count, and the drug is given again, and so on and so forth until the clinical effect is satisfactory.
Adverse reactions:
1. Bone marrow suppression: leukopenia, thrombocytopenia, anemia, sometimes bleeding tendency, bone marrow suppression, pancytopenia, etc., so peripheral blood examinations should be performed weekly for at least 6 weeks after each administration, and appropriate treatment should be given if abnormalities are found. 2. Interstitial pneumonia and pulmonary fibrosis: interstitial pneumonia and pulmonary fibrosis occasionally occur. 3. Allergies: Sometimes rashes occur. If such allergic symptoms occur, the drug should be discontinued. 4. Liver: Sometimes AST, ALT, etc. increase. 5. Kidney: Sometimes BUN increases and proteinuria occurs. 6. Digestive tract: Loss of appetite, nausea, vomiting, vomiting, sometimes stomatitis, diarrhea, etc. occur. 7. Others: Sometimes general fatigue, fever, headache, dizziness, cramps, hair loss, hypoproteinemia occur.
Contraindications:
The following patients are prohibited from using this product: 1. Patients with bone marrow function suppression (it has been reported that adverse reactions such as leukopenia and bone marrow function suppression may occur). 2. Patients with a history of severe allergies to this product.

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