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Nimodipine

Effects and efficacy:
It is used to prevent and treat ischemic damage to brain tissue caused by cerebral vasospasm caused by subarachnoid hemorrhage, improve memory impairment in patients with senile brain damage, and can also be used for ischemic cerebrovascular disease, migraine, sudden deafness, and mild to moderate hypertension. This product can treat and improve senile brain dysfunction, such as memory loss, orientation and attention disorders, and mood swings.

Usage and dosage:
When taking nimodipine, you should strictly follow the doctor’s instructions under the guidance of a doctor; at the same time, you should monitor blood pressure and heart rate, and check liver function regularly. Patients with impaired liver function should monitor the above indicators more closely when taking nimodipine. The injection form is used to prevent and treat ischemic nerve damage caused by cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Please follow the doctor’s advice for details. Preventive medication: Intravenous treatment should be started within 4 days after bleeding, and continuous administration should be given during the maximum risk period of vasospasm, such as 10-14 days after subarachnoid hemorrhage. If the cause of bleeding is surgically removed during the prophylactic use of nimodipine, intravenous infusion of this product should be continued for at least 5 days after surgery. After the end of intravenous infusion treatment, it is recommended to continue oral nimodipine tablets for 7 days, taken every 4 hours (60 mg each time, 6 times a day). Therapeutic medication: If ischemic neurological damage caused by vasospasm has occurred after subarachnoid hemorrhage, treatment should be started as soon as possible and should be continued for at least 5 days and up to 14 days. It is then recommended to take oral nimodipine tablets for 7 days, taken every 4 hours (60 mg each time, 6 times a day). If the bleeding site has been surgically treated during the use of nimodipine injection for prevention or treatment, continue to use this product for infusion treatment for at least 5 days after surgery. Note: Incompatibility: Since the active ingredient of nimodipine can be absorbed by polyvinyl chloride (PVC), only polyethylene (PE) infusion tubes are allowed when infusing nimodipine. The active ingredients of nimodipine injection are slightly light-sensitive and should be avoided from direct sunlight. If used under scattered sunlight or artificial light, no special protective measures are required within 10 hours of infusion. Patients should not be exposed to light for too long during infusion, and appropriate protective measures should be taken (such as using an infusion pump and infusion tube with a light-shielding material cover, and using a colored infusion tube). Oral preparation Ischemic cerebrovascular disease: Oral, 30-120 mg (1.5-6 tablets) per day, divided into 3 doses, for 1 month. Please follow the doctor’s advice for details. Migraine: Oral, 40 mg (2 tablets) once, 3 times a day, 12 weeks as a course of treatment (effectiveness of 88%), about half of the cases can be basically cured or significantly effective, and it can reduce the pain level, frequency and duration of attacks, and prevent the occurrence of premonitory symptoms for vascular, tension, cluster and mixed headaches. Please follow the doctor’s advice for details. Cerebral vasospasm caused by subarachnoid hemorrhage: Oral, 40-60 mg (2-3 tablets) once, 3-4 times a day, 3-4 weeks as a course of treatment. For patients who need surgery, stop taking the medicine on the day of surgery and continue taking it later. Please follow the doctor’s advice for details. Senile brain dysfunction: Unless otherwise prescribed, the recommended dose is 30 mg each time (1 tablet at a time), 3 times a day. Take the whole tablet with a small amount of water, regardless of meal time. After taking nimodipine tablets orally for several months, it is necessary to re-evaluate whether there are still indications for treatment. Please follow the doctor’s advice for details. Sudden deafness: Oral, 40-60 mg (2-3 tablets) a day, taken three times, 5 days as a course of treatment, generally 3-4 courses of medication. Please follow the doctor’s advice for details. Mild and moderate hypertension: Patients with hypertension and the above-mentioned cerebrovascular diseases can be given priority. Oral start 40 mg (2 tablets) once, 3 times a day, the maximum daily dose is 240 mg (12 tablets). Please follow the doctor’s advice for details.

Contraindications:
Contraindicated if allergic to this product. Use with caution during pregnancy and lactation.
Related dosage forms:
Tablets, dispersible tablets, sustained-release tablets, capsules, injections

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