Nicardipine hydrochloride is a vasodilator, and its common dosage forms are tablets and injections. Nicardipine hydrochloride tablets and nicardipine hydrochloride sustained-release tablets are used alone or in combination with other drugs to treat hypertension and exertional angina pectoris; nicardipine hydrochloride injection, nicardipine hydrochloride injection, and nicardipine hydrochloride glucose injection are used for emergency treatment of abnormal hypertension during surgery and hypertensive emergencies; nicardipine hydrochloride sodium chloride injection is suitable for short-term treatment of hypertensive patients who are not suitable or cannot be treated orally. In order to achieve long-term blood pressure control, patients should switch to oral treatment as long as the clinical situation permits.
Nicardipine hydrochloride is a dihydropyridine calcium channel blocker (slow channel blocker or calcium ion antagonist), which can inhibit the transmembrane calcium ion influx of myocardial and vascular smooth muscle without changing the blood calcium concentration, blocking the influx of calcium ions into vascular smooth muscle cells, thereby dilating blood vessels and lowering blood pressure.
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