Mounjaro 替尔泊肽

Tirzepatide is a new type of hypoglycemic drug, a dual agonist of GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. It lowers blood sugar by regulating insulin secretion, delaying gastric emptying and suppressing appetite, and may also assist in weight loss. It is suitable for blood sugar control in patients with type 2 diabetes and should be used under doctor’s orders.

Mechanism of action and characteristics
Dual receptor agonism: Activates GLP-1 and GIP receptors at the same time, enhances insulin secretion and reduces glucagon release, improving blood sugar levels.
Delaying gastric emptying: Prolongs satiety, reduces food intake, and may reduce weight.
Cardiovascular protection potential: Some studies have shown that it may reduce the risk of cardiovascular events, but more evidence is needed.
Applicable population and contraindications
Applicable: Adult patients with type 2 diabetes, especially those with obesity or who need comprehensive metabolic management.
‌Contraindications‌: It is contraindicated for patients who are allergic to the ingredients, type 1 diabetes, and diabetic ketoacidosis; patients with severe gastrointestinal diseases and a history of pancreatitis should use it with caution.
Precautions for use of the drug
‌ Dosage‌: Subcutaneous injection once a week, the dose needs to be adjusted according to the doctor’s instructions.
‌ Side effects‌:
Common: nausea, diarrhea, decreased appetite, usually alleviated with prolonged medication.
Severe: Rare risk of pancreatitis and thyroid C-cell tumors (suggested by animal experiments), symptoms such as abdominal pain and neck lumps require immediate medical attention.
Medication guidance and suggestions
‌ Adjust the dose according to the doctor’s instructions‌: The initial dose is low, and it is gradually increased to reduce gastrointestinal reactions.
‌ Combined lifestyle intervention‌: Dietary control and regular exercise are required during medication to improve the efficacy.
‌ Regular monitoring‌: Including blood sugar, liver and kidney function and weight changes, long-term use requires attention to thyroid function.
Usage recommendations
Telportide is a prescription drug and must be used after evaluation by a doctor. It cannot be replaced or stopped on its own. If blood sugar control is not up to standard or adverse reactions occur, you should seek medical attention and adjust your plan in time. In addition, drugs cannot replace comprehensive diabetes management (such as diet, exercise and control of underlying diseases).