Used to improve postprandial hyperglycemia in patients with type 2 diabetes (limited to patients who cannot effectively control blood sugar through diet and exercise therapy or who still cannot effectively control blood sugar after adding alpha-glucosidase inhibitors on the basis of diet and exercise therapy) patient).
Mitiglinide binds to the sulfonylurea receptor of pancreatic islet β cells and inhibits the ATP-sensitive K+ channel on the pancreatic β cell membrane, causing cell depolarization and an increase in intracellular Ca2+ concentration, thereby promoting insulin secretion and lowering blood sugar.
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