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Metformin Hydrochloride and Glipizide Tablets

Metformin and glipizide tablets have hypoglycemic effects and are a type of diabetes treatment drug that are usually used for the initial treatment of type 2 diabetes.

It is suitable for patients with type 2 diabetes who cannot fully and effectively control blood sugar with diet and exercise therapy.

Metformin Glipizide Tablets are a compound preparation of glipizide and metformin hydrochloride. The two drugs improve blood sugar control in patients with type 2 diabetes through complementary mechanisms of action. Glipizide specifically binds to the sulfonylurea receptor on the B cell membrane, thereby closing the ATP-dependent K* channel, causing depolarization of the membrane potential, opening the Ca²+ channel, and increasing the intracytoplasmic Ca²+ concentration. , prompting insulin secretion to lower blood sugar. Metformin hydrochloride can improve glucose tolerance and reduce basal and postprandial blood sugar in patients with type 2 diabetes.