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Isupagglutide α injection 依苏帕格鲁肽α注射液

Isupagglutide α injection
Isupagglutide α injection is a long-acting hypoglycemic drug developed based on the principle of glucagon-like peptide-1 (GLP-1) receptor agonist. It is mainly used for blood sugar control in adult patients with type 2 diabetes and may have cardiovascular benefits. It must be used according to the doctor’s advice and cannot replace insulin treatment.

1. Drug category and mechanism of action
GLP-1 receptor agonist: stimulates insulin secretion, inhibits glucagon release, and delays gastric emptying by simulating the intestinal hormone GLP-1, thereby lowering blood sugar.
Long-acting dosage form: prolongs the drug’s action time through molecular modification, usually injected once a week.
2. Indications and applicable population
Adult type 2 diabetes: as an adjunct to diet and exercise, it is used for patients with poor blood sugar control.
Patients with high cardiovascular risk: Some GLP-1 drugs have been shown to reduce the risk of cardiovascular events, but they need to be evaluated in combination with the specific situation of the patient.
3. Usage and precautions
Injection method: subcutaneous injection, common sites are abdomen, thigh or upper arm, and must be operated according to the instructions or doctor’s instructions. 1.
Dose adjustment: The initial dose is low, and it is gradually increased to reduce gastrointestinal side effects. The doctor’s instructions must be strictly followed. 2.
Contraindications: Patients with a history of medullary thyroid cancer and multiple endocrine neoplasia type 2 (MEN2) are prohibited from using this drug; patients with pancreatitis and renal insufficiency should use it with caution. 3.
IV. Common side effects and responses
Gastrointestinal reactions: Nausea, diarrhea, vomiting, etc. are mostly temporary and alleviated with prolonged medication.
Risk of hypoglycemia: Blood sugar needs to be monitored when used in combination with other hypoglycemic drugs (such as sulfonylureas and insulin).
Rare and severe reactions: The risk of pancreatitis and thyroid C-cell tumors should be vigilant. See a doctor immediately if symptoms such as abdominal pain and neck lumps occur.
V. Storage and medication instructions
Storage conditions: Refrigerate at 2-8℃ when unopened, and store at room temperature (usually not exceeding 30℃) after opening, and avoid freezing.
Medical tips: Regularly check blood sugar, liver and kidney function and thyroid indicators during medication; pregnant, lactating or planning pregnancy should inform the doctor in advance.
Note: This product is a prescription drug. The specific treatment plan needs to be formulated by the doctor based on the patient’s individual situation. Do not adjust the dosage or stop taking the drug on your own.

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