Iohexol Injection

Effects and efficacy: This product is suitable for injection into blood vessels and body cavities of adults and children. It is used for clinical angiography (cerebral angiography, coronary angiography, peripheral and visceral artery angiography, ventriculography), enhanced CT angiography of the head and body, intravenous urography (IVP), arthrography, endoscopic retrograde pancreaticocholangiography (ERCP), percutaneous transhepatic cholangiography (PTC), hernia or fistula angiography, gastrointestinal angiography, “T” line duct angiography, etc. Dosage and administration: The dosage depends on the type of examination, the patient’s age, weight, cardiac output and general condition, and the technology used. The same drugs produced by different manufacturers may have inconsistent instructions. The above content is referenced from: National Pharmacopoeia Committee. Instructions for Clinical Drug Use in the People’s Republic of China: Chemical Drugs and Biological Products Volume. 2015 Edition. [M]. China Medical Science and Technology Press, 2017: 1218, Iohexol Injection (Beijing Beilu Pharmaceutical Co., Ltd.) Drug Instructions, National Medicine Standard H20053800, Yang Baoxue, Zhang Lan. Practical Clinical Pharmacology [M]. Beijing: China Medical Science and Technology Press, 2018: 812. If you find that the contents of the drug instructions are inconsistent before taking the drug, please consult a doctor or pharmacist in time.
Adverse reactions:
A small number of patients may have some mild reactions, such as: short-term warmth, slight pain, flushing, nausea/vomiting, mild chest pain, skin itching and urticaria. Headache, nausea and vomiting are the most common adverse reactions in myelography. Severe headache lasting for several days may occur intermittently. Other mild adverse reactions found so far include short-term dizziness, back pain, neck pain or pain in the limbs, and various paresthesias. EEG recordings have also shown unclear short-term changes (slow waves). Aseptic meningitis has been found after myelography with water-soluble contrast agents. Similar situations have been reported for myelography using this product, but they are very mild and short-lived. There are also reports of delayed adverse reactions in some patients within hours to days after the contrast. Serious adverse reactions rarely occur, but shock, convulsions, coma, severe laryngeal edema or bronchospasm, renal failure, and death have also been reported. According to statistics on 300,000 cases collected by Professor Katayama of Japan, the incidence of mild adverse reactions to non-ionic contrast agents (including iohexol) is about 3.08%, the incidence of moderate adverse reactions is about 0.04%, and the incidence of severe adverse reactions is about 0.004%.
Drug contraindications:
Allergic to this product is prohibited. It is prohibited during pregnancy. It should be used with caution during lactation. It should be used with caution in patients with liver and kidney dysfunction.