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Functions and indications:
Used to treat malignant malaria, vivax malaria and malaria malaria that are sensitive to chloroquine. It can also be used for the inhibitory prevention of malaria symptoms. It can also be used to treat extraintestinal amebiasis, connective tissue diseases, photosensitivity diseases (such as sunburn erythema), etc. When using an injectable dosage form, switch to oral medication after the condition improves.

Usage and Dosage:
This product has a variety of dosage forms and specifications. The same medicine produced by different manufacturers may have inconsistent instructions. Please read the drug instructions carefully before taking the medicine and take the medicine as prescribed by the doctor. 1. The dosage is based on aminoquine. 300 mg of aminoquine is equivalent to 500 mg of phosphate or 400 mg of sulfate, and 40 mg of aminoquine is equivalent to 50 mg of hydrochloride. 2. For the treatment of malaria caused by Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium falciparum strains that still retain sensitivity, adults or children are given a total of about 25 mg/kg within 3 days. One method of administration is to give 10 mg/kg for the first time on the first day, and then give 5 mg/kg after 6-8 hours; give 5 mg/kg every day for the next two days. Another method is to give 10 mg/kg each on the first two days and 5 mg/kg on the third day. Sometimes adults can also use the following method: give 600 mg at the beginning, 300 mg after 68 hours, and then 300 mg every day for 2 consecutive days. 3. For patients with severe conditions who cannot take the medicine orally, slow intravenous drip can be used, with a total of 25 mg/kg. The first dose is 10 mg/kg, which should be dripped for at least 8 hours. In the next 24 hours, it is divided into 3 doses, 5 mg/kg each time, and all are infused in about 8 hours. The diluent is 0.9% sodium chloride injection. 4. If intravenous drip is not possible, it can also be administered subcutaneously or intramuscularly. Give 2.5mg/kg once every 4 hours, or 3.5mg/kg once every 6 hours, until the total amount reaches 25mg/kg. 5. For prevention of malaria during the epidemic period, adults living in epidemic areas take 300mg orally once a week, and children take 5mg/kg. After leaving the epidemic area, take the same dose for a total of 4-6 weeks. 6. For the treatment of hepatic amoebiasis, adults take 600mg orally every day for the first 2 days, and then 300mg every day for 2-3 weeks. Children take 10mg/kg every day for 2-3 weeks. The maximum daily dose should not exceed 300mg. 7. For the treatment of lupus erythematosus and rheumatoid arthritis, adults can take 300mg orally every day for 7-10 days, and then change to 150mg every day. Continue to take it according to the condition.

Adverse reactions:
1. Oral administration generally causes dizziness, headache, blurred vision, loss of appetite, nausea, vomiting, abdominal pain, diarrhea, rash, tinnitus, irritability, etc., which generally disappear on their own after stopping the drug. 2. In the treatment of paragonimiasis, clonorchiasis and connective tissue diseases, large dosage and long course of treatment may cause severe reactions, the most common of which is ocular toxicity. 3. Because this drug can be secreted by the lacrimal glands and absorbed by the cornea, diffuse white particles appear on the cornea, which can disappear after stopping the drug. 4. Some drugs can accumulate in tissues. Long-term use can cause mild retinal edema and pigment aggregation, dark spots, and affect vision, which is often irreversible. 5. Damage to hearing. Pregnant women taking large amounts can cause congenital deafness and mental retardation in children. 6. Occasionally, it can cause inhibition of the sinus node, leading to arrhythmia and shock. In severe cases, Adams syndrome may occur, leading to death. 7. It can cause drug-induced psychosis. 8. It can also cause various rashes such as lichenoid, maculopapular, and measles-like. Patients who receive long-term treatment or take large doses of the drug may have pigment changes such as gray hypopigmentation or blue-black hyperpigmentation on the skin or hair. 9. Rare hemolysis, aplastic anemia, reversible agranulocytosis and thrombocytopenia.

1. Pregnant women. 2. People who are allergic to this drug.