Goserelin Acetate Sustained-Release Depot ;

Effects and efficacy:
Applicable to breast cancer in premenopausal and perimenopausal women who can be treated with hormones. Applicable to male prostate cancer who can be treated with hormones, it is one of the main choices for prostate cancer drug castration therapy (an elimination endocrine therapy that can reduce or block the effect of hormones on tumors and inhibit tumor growth); evidence-based evidence shows that this product treatment throughout the entire prostate cancer treatment process can improve patient survival, improve life treatment, and reduce the risk of death in patients with advanced prostate cancer by 20%. It can also be used to relieve the symptoms of endometriosis in women, including relieving pain and shrinking endometriosis lesions.
Usage and dosage:
Conventional usage: 3.6 mg dosage form per vial: subcutaneous injection in the abdomen, 3.6 mg per vial, once every 28 days (4 weeks). 10.8 mg dosage form per vial (for the treatment of prostate cancer): subcutaneous injection in the abdomen, 10.8 mg per vial, once every 84 days (12 weeks), long-term treatment. There is no uniform standard for the course of treatment. During clinical treatment, the corresponding treatment plan and course should be formulated according to the specific situation of the patient. Please follow the doctor’s advice for details. Endometriosis The treatment time for endometriosis should not exceed 6 months. Since there is no clinical data on long-term treatment, repeated courses should be avoided considering the problem of bone mineral loss. Please follow the doctor’s advice for details. Pretreatment before surgical treatment of dysfunctional uterine bleeding Give this drug 3.6mg per bottle 4 weeks before endometrial resection to thin the endometrium and help surgical treatment. Please follow the doctor’s advice for details. Women with anemia caused by uterine fibroids can be given this drug 3.6mg once every 28 days for 2-3 months, and supplement iron to correct anemia. Please follow the doctor’s advice for details. Infertility Subcutaneous injection of 3.6mg per bottle, and monitor serum estradiol concentration until it drops to the early follicular level. This process usually takes 7-21 days. Please follow the doctor’s advice for details.
Adverse reactions:
Rash and decreased bone density may occur after medication, and mild bruising at the injection site may occur occasionally. Hypersensitivity reactions and pituitary apoplexy may rarely occur. Male patients may experience hot flashes, decreased libido, breast tenderness and tenderness, temporary aggravation of bone pain, etc. Urethral obstruction and spinal cord compression are rare. Female patients may experience hot flashes, sweating, decreased libido, headache, depression, vaginal dryness, vaginal bleeding, changes in breast size, etc. In the first month of injection for female patients, the plasma estradiol level will transiently increase in the initial stage, causing abnormal vaginal bleeding, including increased menstruation and possible irregular uterine bleeding; in addition, the symptoms of endometriosis (pelvic pain, dysmenorrhea) in ≥10% of patients may worsen, usually disappearing within 1-2 weeks. Note: The use of this drug may cause a decrease in bone density. Male patients may experience decreased glucose tolerance when using it, and bone density and blood sugar should be monitored carefully.
Drug contraindications:
Allergic to this product is prohibited. It is prohibited during pregnancy and lactation.