Gentamicin sulfate salt

Effects and efficacy:
Gentamicin is mainly used to treat bacterial infections, especially those caused by Gram-negative bacteria. Oral administration: Suitable for the treatment of bacterial dysentery or other bacterial intestinal infections, and can also be used for preparation before colon surgery; it can also be used to treat chronic gastritis, and can be combined with anti-ulcer drugs to treat Helicobacter pylori infection of peptic ulcer. Injection: Used to treat severe infections caused by sensitive bacteria, such as neonatal sepsis, septicemia, respiratory tract infection, peritonitis, biliary tract infection, urogenital system infection (except for the initial treatment of simple urinary tract infection), skin and soft tissue infection, burn infection, etc.; it can also be used for central nervous system infections caused by sensitive bacteria, such as meningitis and ventriculitis, and this product can be used for intrathecal injection as an auxiliary treatment. Eye medication: It can be used for conjunctivitis, blepharitis, meibomian adenitis, etc.
Dosage and Administration:
For the treatment of bacillary dysentery or other bacterial intestinal infections, and for preparation before colon surgery. Tablets, effervescent tablets, and enteric-coated tablets: Oral, 240-640 mg per day for adults, divided into 4 doses; 5-10 mg/kg per day for children, divided into 4 doses according to body weight. Granules: Oral, 80-160 mg per time for adults, 3-4 times a day; 10-15 mg/kg per day for children, divided into 3-4 doses according to body weight. Sustained-release tablets for the treatment of chronic gastritis, Helicobacter pylori infection, and mild acute enteritis: Oral, 80 mg per time, twice a day. The course of treatment for mild acute enteritis is 3-5 days; for Helicobacter pylori infection of the stomach and duodenum, the course of treatment is 3-4 weeks. Take 1 hour after meals. For adults with severe infections: intramuscular injection or intravenous drip after dilution, 80 mg (80,000 units) per time, or 1-1.7 mg/kg per time according to body weight, once every 8 hours; or 5 mg/kg per time, once every 24 hours. The course of treatment is 7-14 days. Children: Intramuscular injection or intravenous drip after dilution, 2.5 mg/kg once, once every 12 hours; or 1.7 mg/kg once, once every 8 hours. The course of treatment is 7-14 days, during which the blood drug concentration should be monitored as much as possible, especially for newborns or infants. When intravenously dripping, add a single dose to 50-200 ml of 0.9% sodium chloride injection or 5% glucose injection. The amount of liquid added for intravenous drip once a day should be no less than 300 ml, so that the concentration of the drug solution does not exceed 0.1%. The solution should be dripped slowly within 30-60 minutes to avoid neuromuscular blocking effects. For intrathecal and intraventricular administration of central nervous system infections: 4-8 mg for adults once, 1-2 mg for children (over 3 months old), once every 2-3 days. When injecting, dilute the drug solution to a concentration not exceeding 0.2%, draw it into a 5ml or 10ml sterile syringe, and after lumbar puncture, let a considerable amount of cerebrospinal fluid flow into the syringe first, draw and push, and slowly inject all the drug solution within 3-5 minutes. For ocular medication for conjunctivitis, blepharitis, and meibomian gland inflammation: drip this product into the eyelid, 1-2 drops at a time, 3-5 times a day. The dosage for patients with renal impairment is injected once every 8 hours for patients with normal renal function, and the normal dose is 1-1.7mg/kg at a time; when the creatinine clearance rate is 10-50ml/min, once every 12 hours, 30-70% of the normal dose at a time; when the creatinine clearance rate is <10ml/min, 20-30% of the normal dose is given every 24-48 hours. After hemodialysis, according to the severity of the infection, adults can be supplemented with a dose of 1-1.7mg/kg per body weight, and children (over 3 months old) can be supplemented with 2-2.5mg/kg at a time. Contraindications: Contraindicated for those who are allergic to this product. Use with caution in children. Use with caution during pregnancy. Use with caution during lactation. Use with caution for renal impairment. Related dosage forms: Tablets, effervescent tablets, enteric-coated tablets, sustained-release tablets, granules, injection