Indications
This drug is used to treat adult patients with relapsed or refractory multiple myeloma who have progressed after at least three lines of treatment (at least one proteasome inhibitor and immunomodulator). [1]
Pharmacokinetics
Ikioren injection is an autologous immune cell injection that uses a lentiviral vector to integrate the chimeric antigen receptor (CAR) gene targeting B cell maturation antigen (BCMA) into the patient’s own peripheral blood CD3-positive T cells. After being infused back into the patient’s body, it kills tumor cells by recognizing the BCMA target on the surface of multiple myeloma cells. [1]
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