Effects and efficacy: Mainly used for advanced breast cancer and colorectal cancer. It can be used as a rescue treatment for breast cancer after failure of anthracycline and taxane treatment.
Usage and dosage: The recommended dose of capecitabine is 1250mg/m2, taken orally twice a day (once in the morning and evening: equal to a total daily dose of 2500mg/m2). Stop the drug for 1 week after 2 weeks of treatment, and 3 weeks is a course of treatment. Capecitabine tablets should be swallowed with water within 30 minutes after a meal. When used in combination with docetaxel, the recommended dose of capecitabine is 1250mg/m2, twice a day, and stop the drug for 1 week after 2 weeks of treatment. The recommended dose of docetaxel used in combination with it is 75mg/m2, once every 3 weeks, intravenous drip for 1 hour. According to the instructions for docetaxel, some chemotherapy adjuvant drugs should be routinely used before using docetaxel in patients receiving combined chemotherapy with capecitabine and docetaxel. When used in combination with oxaliplatin, capecitabine treatment can be started on the same day after the patient is given oxaliplatin (dose of 130 mg/m2, intravenous infusion for 2 hours), with a dose of 1000 mg/m2, twice a day, and stop for 1 week after 2 weeks of treatment. When used for adjuvant treatment of patients with Dukes’ C stage colon cancer, the recommended treatment time is 6 months, that is, capecitabine 1250 mg/m2, taken orally twice a day, stop for 1 week after 2 weeks of treatment, 3 weeks as a course of treatment, a total of 8 courses (24 weeks).
Adverse reactions:
Adverse reactions may occur when capecitabine is used as a single drug for different indications (adjuvant treatment of colon cancer, treatment of metastatic colorectal cancer and metastatic breast cancer) and in combination chemotherapy regimens. Among them, the common adverse reactions of capecitabine combined with different chemotherapy regimens are as follows:
Drug contraindications:
Allergy to this product is prohibited. It is prohibited during pregnancy. It is prohibited during lactation. It is prohibited for renal function impairment.
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