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Bumetanide

Effects and efficacy:
Used to treat edematous diseases, including congestive heart failure, cirrhosis, kidney disease (nephritis, nephropathy and acute and chronic renal failure caused by various reasons), especially when other diuretics (such as furosemide) are ineffective, this type of drug may still be effective; it can also be used in combination with other drugs to treat acute pulmonary edema and acute cerebral edema. Used to treat hypertension. In the step therapy of hypertension, this product is not the first choice for the treatment of essential hypertension. However, when thiazide drugs are ineffective, especially when accompanied by renal insufficiency or hypertensive crisis, this type of drug is particularly suitable. Used to prevent acute renal failure, it can be used for various reasons leading to insufficient renal blood perfusion, such as dehydration, shock, poisoning, anesthesia accidents and circulatory insufficiency. Timely use of this product while correcting insufficient blood volume can reduce the chance of acute tubular necrosis. Used for hyperkalemia and hypercalcemia. Used for dilutional hyponatremia, especially when the blood sodium concentration is lower than 120mmol/L. Used for hypersecretion of antidiuretic hormone (SIADH). Used for acute drug or poison poisoning, such as barbiturate poisoning. Bumetanide may still be effective in some cases where furosemide is ineffective.

Usage and Dosage:
For specific usage and dosage for different populations and different diseases, consult doctors and pharmacists, and refer to the drug instructions of different preparations. Oral preparations for adults: For the treatment of edematous diseases or hypertension, oral administration starts at 0.5~2mg (half a tablet to 2 tablets) per day, and repeats every 4~5 hours if necessary. The maximum dose can reach 10~20mg (10~20 tablets) per day. The medication can also be taken at intervals, that is, 1 day of medication every 1-2 days. Children: Oral, 0.01~0.02mg/kg per body weight, once every 4~6 hours if necessary. Injection: The intravenous injection concentration is generally 0.1mg/ml, and the intramuscular injection concentration is 0.25~0.5mg/ml. For adults to treat edema or hypertension, the starting dose is 0.5-1 mg intravenously or intramuscularly, and repeated every 2-3 hours if necessary, with a maximum daily dose of 10 mg; for acute pulmonary edema, the starting dose is 1-2 mg intravenously, and repeated every 20 minutes if necessary, or 2-5 mg diluted and slowly dripped (drip time is not less than 30-60 minutes). For children, the intramuscular or intravenous injection is 0.01-0.02 mg/kg per body weight, and once every 4-6 hours if necessary.

Drug contraindications:
Allergy to this product is prohibited. It is prohibited during pregnancy. It is used with caution during lactation. It is used with caution by athletes
Related dosage forms:
Tablets, injections, powder for injection

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