Etanercept injection is a competitive inhibitor of cell surface tumor necrosis factor receptors. Its main clinical indications are rheumatoid arthritis and ankylosing spondylitis.
Rheumatoid arthritis: It can be used for adult patients with moderate to severe active rheumatoid arthritis. When DMARDs (disease-modifying antirheumatic drugs) including methotrexate (if not contraindicated) are ineffective, etanercept can be used in combination with methotrexate for treatment. It has been shown that etanercept, when used alone or in combination with methotrexate, can reduce the rate of progression of joint damage in the X-ray detection phase and improve joint function.
Ankylosing spondylitis: It can be used for adult patients with severe active ankylosing spondylitis. Etanercept can be used for treatment when conventional treatment is ineffective.
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