Effects and efficacy:
Carboplatin injection is a second-generation platinum anti-tumor drug, which has certain effects on ovarian cancer, small cell lung cancer, non-small cell lung cancer, head and neck squamous cell carcinoma, esophageal cancer, testicular cancer, seminoma, bladder cancer, mesothelioma, pediatric brain tumors, etc. This product is a non-specific anti-tumor drug for the cycle, which directly acts on DNA, thereby inhibiting tumor cells with vigorous division.
Usage and dosage:
This product can be used alone or in combination with other anti-cancer drugs. Before use, add this product to 250-500ml of 5% glucose injection for dilution. For intravenous infusion, the recommended dose is calculated based on 0.3-0.4g/m2 or AUC per body surface area, a single dose, or five doses for 5 days, repeated every 3-4 weeks, and 2-4 cycles as a course of treatment. The dose after the first dose needs to be adjusted according to the white blood cell and platelet counts after the medication. Please follow the doctor’s advice for details.
Adverse reactions:
Common adverse reactions Myelosuppression is a dose-related toxicity. After a single dose, white blood cells and platelets reach their lowest point 21 days after medication, and usually recover around 30 days after medication; the lowest point of granulocytes occurs 21 to 28 days after medication, and usually recovers around 35 days; white blood cell and platelet reduction is dose-related and has an accumulation effect. Pain at the injection site. Case data and post-marketing experience show that about 15% of patients experience nausea without vomiting after treatment with carboplatin, 65% experience vomiting, and 1/3 of them have severe vomiting; this product also has a certain degree of nephrotoxicity. The incidence and severity of nephrotoxicity may increase in patients with impaired renal function before treatment. Less common adverse reactions Allergic reactions (rash or itching, occasionally wheezing), which occur within a few minutes after use; peripheral neurotoxicity, numbness or tingling of fingers (toes), with cumulative effects; ototoxicity, high-frequency hearing loss occurs first, tinnitus is occasionally seen; blurred vision, mucositis or stomatitis; constipation or diarrhea, lack of appetite, etc. In addition, you may experience other side effects. If you feel unwell after taking the medicine, please inform the doctor in time. The doctor will determine whether to stop taking the medicine or take necessary measures according to the severity of the adverse reaction.
Drug contraindications:
Allergic to this product is prohibited. It is prohibited for liver and kidney dysfunction. It is prohibited to use it with caution during pregnancy and lactation.
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