bupropion hydrochloride sustained release tablets

Effects and efficacy:
Used to treat depression and seasonal affective disorder. Can be used for nicotine addiction and assist in quitting smoking. In addition, it is also clinically used for the treatment of bipolar depression (presupposed that mood stabilizers have been used at the same time) and attention deficit hyperactivity disorder; it also has a certain therapeutic effect on certain sexual dysfunctions.
Usage and dosage:
For the treatment of depressive disorders, oral administration starts with a small dose, with an initial dose of 75 mg once (75 mg per tablet, one tablet at a time), twice a day (once in the morning and once in the evening). After taking it for at least 3 days, according to the clinical efficacy and tolerance, the dose can be gradually increased to 75 mg once (1 tablet), 3 times a day (once in the morning, noon and evening); later, it can be gradually increased to the usual dose of 300 mg per day (75 mg per tablet, 5 tablets), 3 times a day (2 tablets in the morning, 1 tablet in the afternoon and 1 tablet in the evening). During the dosage increase process, the dosage increase within 3 days shall not exceed 100 mg per day. As an antidepressant, this product usually takes 2-4 weeks to show obvious effects. If there is no obvious effect after several weeks of continuous use, you can consider gradually increasing it to a maximum daily dose of 450mg (400 for long-acting agents), but the maximum dose each time should not exceed 150mg (2 tablets), and the interval between two doses should not be less than 6 hours. Please follow the doctor’s advice for details. Start taking this product 1-2 weeks before quitting smoking, with a starting dose of 75mg once, once in the morning and once in the evening; after 3 days, it can be increased to 75mg, 3 times a day, and you can consider gradually increasing it to a maximum daily dose of 300mg. Please follow the doctor’s advice for details. For the treatment of children with hyperactivity-attention deficit disorder, reduce the starting dose and each additional dose, and the maximum daily dose should not exceed 300mg. Please follow the doctor’s advice for details.
Adverse reactions:
One of the most common adverse reactions in clinical practice is insomnia. Other common adverse reactions include agitation, dry mouth, facial flushing, abdominal pain, headache/migraine, nausea and vomiting, anorexia, constipation, sweating, tinnitus, rash, tremor and blurred vision. Most adverse reactions occur quickly, but they often disappear over time. Occasionally, there is weight gain and sedation. Serious adverse reactions: Rarely, there is hepatotoxicity, changes in the hematopoietic system, and severe headaches; rarely, there is epileptic seizure, inducing mental symptoms, such as hypomania (more common in patients with bipolar disorder, but less common than other antidepressants), suicidal thoughts and behaviors.
Drug contraindications:
Allergic to this product is contraindicated. Use with caution in patients with liver and kidney dysfunction. Use with caution during pregnancy and lactation.